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Tuesday, February 3, 2015

Mixed or Lobular-predominant Panniculitis

There are only a few causes of septal panniculitis, ie SEAptal
- Scleroderma
- Erythema nodoSum (the 'S' reminds you it's septal)
- a-AT deficiency 

The other big group of panniculitis is the mixed / lobular pattern.  If you read Bolognia pg1641, the authors seemed SKEPTICAL about dichotomising panniculitides as such. 

Stasis - Lipodermatosclerosis 
Kids - Sclerema neonatorum, Fat necrosis of the newborn (needle-shaped clefts within lipocytes)
Erythema induratum (a/w vasculitis of sub-Q vessels) 
Pancreatitis (necrosis is an early feature) 
Traumatic - blunt trauma, injectable substances, cold panniculitis, sclerosing lipogranuloma
Infectious 
CTDs / Autoimmune - Dermatomyositis, Lupus 
Lipodystrophies

from Dermatology 3ed, Bolognia (eds)

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