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Monday, February 2, 2015

Drug Causes of Pseudoporphyria - FATTeND

Pseudoporphyria demonstrates identical clinical (blisters, erosions, scarring/milia on sun exposed sites) and histological (cell-poor sub-epidermal blister, dermal festooning, caterpillar bodies, eosinophilic hyaline deposits around BV, DIF+ along the BMZ and perivascularly) features to Porphyria Cutanea Tarda (defect in Uroporphyrinogen Decarboxylase).

Risk factors include:
  1. Dialysis
  2. Use of tanning beds (UVA)
  3. Drugs - FATTeND
Fluoroquinolones
Amiodarone
Tretinoin (and other Retinoids)
TEtracyclines
Naproxen and other NSAIDs
Diuretics (Loop and Thiazide)
at 6:53 PM
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