WELCOME !!

Just a few words to start off, I wouldnt' dare claim credit for ALL the mnemonics on this blog. In fact, a number of the cleverer mnemonics you see either are the good work of other doctors/students or have been shamelessly lifted out of medical books.

If you've got a medical mnemonic gem to contribute, feel free to submit it to dingydingding(at)googlemail(dot)com

Last but not least, please feel free to point out any errors or improvements that can be made in any of the mnemonics!! Otherwise, you can always click on the ad-links too if you wanna do your part =P

Monday, September 1, 2008

Precipitants of hepatic encephalopathy - HEPATICS

this mnemonic's pretty neat... got it from RxPG online and made some changes. enjoy!

Precipitants of Hepatic Encephalopathy - HEPATICS

Haemorrhage in the GI tract
Electrolyte disturbances (incl hypoNa+, hypoK+, hypovolaemia, acid/alkalosis, hypoxia)
Protein in the diet
Azotemia
TIPSS (transjugular intrahepatic porto-systemic shunt)
Infection (eg. spontaneous bacterial peritonitis)
Constipation
Sedatives (eg. opiates, benzos)

Inducers 'n' Inhibitors

Drug interactions are a bitch to study =(....

Hepatic enzyme INDUCERS - PC BRAS

Phenytoin
Carbamazepine

Barbiturates
Rifampicin
Alcohol (chronically)
Sulfapyrazine


so that's why they call them inducers......

Hepatic enzyme INHIBITORS - MAGIC VASES

M
acrolides
Azoles (incl metronidazole)
Grapefruit
Isoniazid
C : cimetidine, chloramphenicol, ciprofloxacin

Valproate
Amiodarone
SSRIs
Esomeprazole
Sulphonamides

note that 'MAGIC VASES' isn't an exhaustive list; majority of drugs are enzyme inhibitors anyways, both pharmacokinetically and pharmacodynamically, rather than inducers