Drug interactions are a bitch to study =(....
Hepatic enzyme INDUCERS - PC BRAS
Phenytoin
Carbamazepine
Barbiturates
Rifampicin
Alcohol (chronically)
Sulfapyrazine
so that's why they call them inducers......
Hepatic enzyme INHIBITORS - MAGIC VASES
Macrolides
Azoles (incl metronidazole)
Grapefruit
Isoniazid
C : cimetidine, chloramphenicol, ciprofloxacin
Valproate
Amiodarone
SSRIs
Esomeprazole
Sulphonamides
note that 'MAGIC VASES' isn't an exhaustive list; majority of drugs are enzyme inhibitors anyways, both pharmacokinetically and pharmacodynamically, rather than inducers
Monday, September 1, 2008
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